2021年

QFR的FAVOR III China，国际首个造影FFR大型RCT研究，在顶级权威杂志《柳叶刀》发表

Xu B, Tu S, Song L, et al, FAVOR III China study group. Angiographic quantitative flow ratio-guided coronary intervention (FAVOR III China): a multicentre, randomised, sham-controlled trial. Lancet. 2021 Nov 3;S0140-6736(21)02248-0. doi: 10.1016/S0140-6736(21)02248-0.

UFR验证研究，国际首个商用基于腔内影像IVUS的FFR产品的临床验证研究在国际心血管顶级权威期刊Circulation介入子刊发表

Yu W , Tanigaki T, Ding D, Wu P , Du H , Ling L; Huang B , Li G , Yan W , Zhang S , Yan F, Okubo M, Matsuo H , Wijns W, Tu S. Accuracy of intravascular ultrasound-based fractional flow reserve in identifying hemodynamic significance of coronary stenosis Circulation. Circ Cardiovasc Interv. 2021 Feb;14(2):e009840. doi: 10.1161/CIRCINTERVENTIONS.120.009840. Epub 2021 Feb 5. PMID: 33541105

2020年

FAVOR III China，，国际首个造影FFR大型RCT研究设计文章发表发表

Song L, Tu S, Sun Z, Wang Y, Ding D, Guan C, et al. Quantitative flow ratio-guided strategy versus angiography-guided strategy for percutaneous coronary intervention: Rationale and design of the FAVOR III China trial. Am Heart J, Inpress, Available online 24 February 2020.

2020/2021年

国际心血管顶级权威期刊欧洲心脏杂志发表两篇综述文章，为至今为止QFR历史上最重要的综述

Tu S, Westra J, Adjedj J, Ding D, Liang F, Holm N. R., Reiber H, Wijins W. Fractional Flow Reserve in clinical practice: from wire-based invasive measurement to image-based computation. European Heart Journal. 2020 Sep 7;41(34):3271-3279.doi: 10.1093/eurheartj/ehz918.

Ding D, Huang J, Westra J, Cohen DJ, Chen Y, Andersen BK, Holm NR, Xu B, Tu S, Wijns W. Immediate post-procedural functional assessment of percutaneous coronary intervention: current evidence and future directions. European Heart Journal. 2021 Apr 5:ehab186. doi: 10.1093/eurheartj/ehab186.

2019年

OFR验证研究，国际首个商用的基于腔内影像OCT的FFR产品的临床验证研究在国际心血管顶级权威期刊EuroInvervention发表

Yu W, Huang H, Jia D, Chen S, Raffel OC, Ding D, Tian F, Kan J, Zhang S, Yan Y, Chen Y, Bezerra HG, Wijns W, Tu S. Diagnostic Accuracy of Intracoronary Optical Coherence Tomography-derived Fractional Flow Reserve for Assessment of Coronary Stenosis Severity. EuroIntervention. 2019 Jun 20;15(2):189-197. doi: 10.4244/EIJ-D-19-00182.

CT-QFR验证研究，博动基于CCTA的FFR产品的临床验证研究在国际心血管顶级权威期刊JACC介入子刊发表

Li Z, Zhang J, Xu L, Yang W, Li G, Ding D, Chang Y, Yu M, Kitslaar P, Zhang S, Reiber JHC, Arbab-Zadeh A, Yan F, Tu S. Diagnostic Accuracy of a Fast Computational Approach to Derive Fractional Flow Reserve From Coronary CT Angiography. JACC Cardiovasc Imaging. 2019 Sep 12. pii: S1936-878X(19)30728-4. doi: 10.1016/j.jcmg.2019.08.003.

2017年

QFR的FAVOR II China，国际首个造影FFR前瞻性、导管室在线临床试验在国际心血管顶级权威期刊JACC发表

Tu S, Qiao S, Qu X, Chen Y, Yang J, Guo L, Sun Z, Li Z, Tian F, Fang W, Chen J, Li W, Guan C, Holm NR, Wijns W, Hu S. Angiography-Based Quantitative Flow Ratio for Online Assessment of Coronary Stenosis: FAVOR II China Study. J Am Coll Cardiol. 2017 Dec 26;70(25):3077-3087. doi:10.1016/j.jacc.2017.10.035.

QFR的FAVOR II Europe-Japan，同年在欧洲和日本完成造影FFR前瞻性、导管室在线临床试验，并在国际心血管顶级权威期刊JAHA发表

Westra J, Andersen BK, Campo G, Matsuo H, Koltowski L, Eftekhari A, Liu T, Serafino LD, Girolamo DD, Escaned J, Nef H, Naber C, Barbierato M, Tu S, Neghabat O, Madsen M, Tebaldi M, Tanigaki T, Kochman J, Somi S, Esposito G, Mercone G, Mejia-Renteria H, Ronco F, Bøtker HE, Wijns W, Christiansen EH, Holm NR. Diagnostic Performance of In-Procedure Angiography-Derived Quantitative Flow Reserve Compared to Pressure-Derived Fractional Flow Reserve: The FAVOR II Europe-Japan Study. J AM HEART ASSOC. 2018;7: e009603. DOI: 10.1161/JAHA.118.009603.

2016年

QFR FAVOR Pilot，完成国际首个回顾性造影FFR与压力导丝FFR的对比临床试验，并在国际心血管顶级权威期刊JACC介入子刊发表

Tu S, Westra J, Yang J, von Birgelen C, Ferrara A, Pellicano M, Nef H, Tebaldi M, Murasato Y, Lansky A, Barbato E, van der Heijden LC, Reiber JH, Holm NR, Wijns W; FAVOR Pilot Trial Study Group. Diagnostic Accuracy of Fast Computational Approaches to Derive Fractional Flow ReserveFrom Diagnostic Coronary Angiography: The International Multicenter FAVOR Pilot Study. JACC Cardiovasc Interv. 2016 Oct 10;9(19):2024-2035. doi: 10.1016/j.jcin.2016.07.013.